It is claimed that an aspirin a day doubles the chances of a long life and aspirin is the most widely used drug in the world [4]. Slightly soluble in cold water. c1ccc(c(c1)C(=O)O)O The melting point is, along with the boiling point, a characteristic property of every substance. Salicylic acid, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant ®, 1.00635 Salicylic acid, fine powder EMPROVE ® ESSENTIAL Ph Eur,BP,USP, 2 Names and Identifiers Expand this section. Food Agric., 85, 2005, 1444-1452. ass: Standard non-polar; Column length: 3.05 m; Column type: Packed; Heat rate: 10 K/min; Start T: 40 C; End T: 250 C; End time: 60 min; Start time: 4 min; CAS no: 69727; Active phase: SE-30; Carrier gas: He; Substrate: Supelcoport and Chromosorb; Data type: Linear RI; Authors: Peng, C.T. Home page ; Blog; V-BLOG; Submit Post; Login; Sign Up; Live Sports; Chemistry Medicine & Drugs Salicylic Acid: Production, Properties & Uses. The melting properties of salicylic acid were determined by differential scanning calorimetry. Anal. Chemical dangers The solution in water is a weak acid. ; Moffat, A.C., Gas-liquid chromatographic retention indices of 1318 substances of toxicological interest on SE-30 or OV-1 stationary phase, J. I have an organic chem lab tomorrow and need some help. The melting point determination apparatus is filled with paraffin and fitted with a thermometer. Soc. CopyCopied, YGSDEFSMJLZEOE-UHFFFAOYSA-N Also, it decomposes at around 200 °C. Salicylic acid is a key ingredient in many skin-care products for the treatment of acne, psoriasis, calluses, corns, keratosis pilaris, and warts. It functions as a plant hormone. 159 °C Wikidata Q193572. This colorless crystalline organic acid is widely used in organic synthesis and functions as a plant hormone. ; Yang, Z.C., Prediction of Retention Indexes I. Structure-Retention Index Relationship on Apolar Columns, J. 2021-01-02. 4-aminosalicylic acid was first synthesized by Seidel and Bittner in 1902. Poly Bottle; 500g. CopyCopied, InChI=1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10) It has the formula C7H6O3. It is a BHA found as a natural compound in plants. Toxicol., 11, 1987, 8-11. ass: Standard non-polar; Column type: Other; CAS no: 69727; Active phase: Methyl Silicone; Data type: Normal alkane RI; Authors: Ardrey, R.E. 229.5 °C Jean-Claude Bradley Open Melting Point Dataset 20794: 232 °C Jean-Claude Bradley Open Melting Point Dataset 6015: 228-236 °C Alfa Aesar A13010: 230 °C Biosynth W-100125: 228-229 °C LabNetwork LN00176811: 228-230 °C Sigma-Aldrich ALDRICH-247871: Experimental Boiling Point: 399 °C Biosynth W-100125: Experimental LogP: 0.914 LabNetwork LN00176811: Experimental Flash Point… J., 9(2), 1976, 69-74. class: Semi-standard non-polar; Column diameter: 0.25 mm; Column length: 30 m; Column type: Capillary; Description: 40C(3min)=> 2C/min=>180C=>10C/min=>250C(5min); CAS no: 69727; Active phase: HP-5MS; Carrier gas: He; Phase thickness: 0.25 um; Data type: Normal alkane RI; Authors: Alissandrakis, E.; Kibaris, A.C.; Tarantilis, P.A. Stockroom Favorite (6) Available on GSA Contract (4) Application. Salicylic acid MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents. The melting point … Sci., 19, 1981, 219-226. ass: Semi-standard non-polar; Column diameter: 0.25 mm; Column length: 30 m; Column type: Capillary; Start T: 60 C; End T: 270 C; CAS no: 69727; Active phase: VF-5MS; Carrier gas: He; Phase thickness: 0.25 um; Data type: Linear RI; Authors: Todua, N.G., Retention Data. Sci. 1.443. Toxicol., 37, 1977, 295-305. ass: Standard non-polar; Column diameter: 0.2 mm; Column length: 20 m; Column type: Capillary; Heat rate: 4 K/min; Start T: 100 C; End T: 230 C; CAS no: 69727; Active phase: SE-30; Data type: Normal alkane RI; Authors: Shakirov, L.G. Light Sensitive. The tube is inserted with the open side into the device in a way that it is positioned alongside the thermometer. You can also browse global suppliers,vendor,prices,Price,manufacturers of Salicylic acid(69-72-7). Protective goggles should be worn during the experi­ ment as salicylic acid must not come in contact with the eyes. there is a question that asks: Would you expect the melting point of the isolated salicylic acid to be lower, higher or the same as stated in the text(159 degrees celsius)???why??? SALICYLIC ACID: ICSC: 0563: PHYSICAL & CHEMICAL INFORMATION; Physical State; Appearance NEEDLE-SHAPED CRYSTALS OR COLOURLESS CRYSTALLINE POWDER. Because of its effect on skin cells, salicylic acid is used in several shampoos used to treat dandruff. Find chemicals information Salicylic acid at guidechem, professional and easy to use. Forens. Storage & Sensitivity. CopyCopied, CSID:331, http://www.chemspider.com/Chemical-Structure.331.html (accessed 03:36, Jan 9, 2021) No new polymorphs or solvates of salicylic acid were found. melting point of salicylic acid is determined in this manner. ; Harizanis, P.C. 211°/20mm. Solubility. Lehmann first tried PAS as an oral TB therapy late in 1944. Combustible. Physical Properties: Melting Point : 158-161 ºC. It is obtained from the bark of the white willow and wintergreen leaves. Quality Management Dossier ; Operational Excellence Dossier; SDS; CoA; Application Notes; Certificates; Material Qualification Dossier; Synonyms: 2-Hydroxybenzoic acid EC Number: 200-712-3 Hill Formula: C₇H₆O₃ CAS #: 69-72-7 Chemical Formula: HOC₆H₄COOH Grade: … The free acid occurs naturally in small amounts in many plants, particularly the various species of Spiraea.The methyl ester also occurs widely in nature; it is the chief constituent of oil of wintergreen. N,N-bis(2-pyridin-2-yl-ethyl)-hydroxylamine (6965-67-9), (2E)-3-methoxy-2-methyl-2-propenoyl isocyanate, (E)-N-(1-cyclopent-3-enylcarbamoyl)-3-methoxy-2-methylprop-2-enamide, ethyl 2-cyano-2-cyclohexylideneacetate (6802-76-2), 1,2,4,5-benzenetetracarbonitrile (712-74-3), 1-(3-chloro-1-azulenyl)-2,2,2-trifluoroethanone, 1-benzyl-3,4-dihydro-1H-1,4-benzodiazepine-2,5-dione, 4,6-dimethyl-1,3,5-triazin-2-yl methyl ether (3599-66-4), 7-hydroxy-8-methyl-4-phenyl-2H-chromen-2-one, 3,3,8-trimethyl-1,5-dihydro[1,3]dioxepino[5,6-c]pyridin-9-ol, 7,8-dimethyl-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one, The Journal of Organic Chemistry, 27, p. 3551, 1962. Melting point / freezing point; Boiling point; Density; Particle size distribution (Granulometry) Vapour pressure; Partition coefficient; Water solubility; Solubility in organic solvents / fat solubility; Surface tension; Flash point; Auto flammability; Flammability; Explosiveness; Oxidising properties; Oxidation reduction potential Salicylic Acid CAS: 69-72-7 Molecular Formula: C7H6O3 Molecular Weight (g/mol): 138.122 MDL Number: MFCD00002439 InChI Key: YGSDEFSMJLZEOE-UHFFFAOYSA-N Synonym: 2-carboxyphenol, duoplant, freezone, keralyt, o-carboxyphenol, o-hydroxybenzoic acid, retarder w, rutranex, salicylic acid, salonil PubChem CID: 338 ChEBI: CHEBI:16914 IUPAC Name: 2-hydroxybenzoic acid … Synonym Chemical Name (s): … ... Melting Point: 158°C: pH: 2.4: Color: White: Boiling Point: 211°C: Quantity: 500g: Chemical Name or Material: Salicylic Acid: Show More Show Less: Safety and Handling Emergency Overview Harmful if swallowed. CopyCopied, Validated by Experts, Validated by Users, Non-Validated, Removed by Users, Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, Predicted data is generated using the US Environmental Protection Agency’s EPISuite™, Click to predict properties on the Chemicalize site, For medical information relating to Covid-19, please consult the. A monohydroxybenzoic acid that is benzoic acid with a hydroxy group at the ortho position. The melting point is, along with the boiling point, a characteristic property of every substance. Nov 14th, 2020 ; LOOKING-X. In experiment C3.1.3.1, the thiele tube is used to determine the melting point of salicylic acid. By Admin Lookingx Jul … 211 °C / 20 mm Hg (372.9924 °C / 760 mmHg) Food and Agriculture Organization of the United Nations 2-Hydroxybenzoic acid. 158-161 °C Sigma-Aldrich SIAL-105910. Salicylic acid melting point Share this page I recently was prescribed 2% salicylic acid face wash Speelac and after using it twice a day for two days my skin … ; Target: Cyclooxygenase?COX? volatile benzenoid biosynthesis I (ester formation), S-adenosyl-L-methionine + salicylate -> methylsalicylate + S-adenosyl-L-homocysteine, salicylate + NADH + oxygen + H+ -> gentisate + NAD+ + H2O, salicylate + UDP-alpha-D-glucose -> salicylate 2-O-beta-D-glucoside + UDP + H+, salicylate + UDP-alpha-D-glucose -> salicylate beta-D-glucose ester + UDP. 158-160° Boiling Point. Chromatogr., 220, 1981, 195-252. ass: Standard non-polar; Column length: 6 ft; Column type: Packed; Heat rate: 8 K/min; Start T: 130 C; End T: 290 C; End time: 8 min; Start time: 2 min; CAS no: 69727; Active phase: SE-30; Carrier gas: N2; Substrate: Chromosorb W AW DMS; Data type: Normal alkane RI; Authors: Peel, H.W. Dates: Modify . Boiling Point : 211 ºC (20 mmHg) Density : 1.44 g/mL. Organic Compound; Ester; Drug; Food Toxin; Plant Toxin; Anti-Infective Agent; Antifungal Agent; Metabolite; Keratolytic Agent; Household Toxin; Natural Compound; Synthetic Compound, ORL-RAT LD50 891 mg kg-1, ORL-MUS LD50 480 mg kg-1, Harmful/Irritant/Corrosive/Light Sensitive, Harmful/Irritant/Corrosive/Light Sensitive/dangerous for environment, P261-P280-P305+P351+P338-P304+P340-P405-P501a, WARNING: Causes GI injury, skin and eye irritation. Salicylic acid (from Latin salix, willow tree) is a lipophilic monohydroxybenzoic acid, a type of phenolic acid, and a beta hydroxy acid (BHA). Applications. ; Perrigo, B., A practical gas chromatographic screening procedure for toxicological analysis, Can.Soc.Forens.Sci.J., 9(2), 1975, 69-74. ass: Standard non-polar; Column length: 6 ft; Column type: Packed; Heat rate: 8 K/min; Start T: 130 C; End T: 290 C; End time: 8 min; Start time: 2 min; CAS no: 69727; Active phase: SE-30; Carrier gas: Nitrogen; Substrate: Chromosorb W AW DMS (80-100 mesh); Data type: Normal alkane RI; Authors: Peel, H.W. It is a crystalline organic carboxylic acid with keratolytic, bacteriostatic and fungicidal properties. On the Anomalous Melting Point and the Decomposition of Acetyl-salicylic Acid. It is derived from the metabolism of salicin. Irritating to eyes, respiratory … The melting properties of salicylic acid were determined by differential scanning calorimetry. Salicylic acid, also called ortho-hydroxybenzoic acid, a white, crystalline solid that is used chiefly in the preparation of aspirin and other pharmaceutical products. the melting point. ; Polissiou, M., Flavour compounds of Greek cotton honey, J. Sci. Tetrahedron Letters, 37, p. 153, 1996. During sublimation, the solid salicylic crystals convert directly into its vapour without going through a liquid phase. The solubility of salicylic acid has been investigated in methanol, acetonitrile, acetic acid, acetone, water, and ethyl acetate from (10 to 50) °C. Create . Water solubility increased by Na3PO4, alkali acetates or alkali citrates, White to faint yellow crystalline powder; faint nutty odour. ; Peel, H.W., The use of retention indices and temperature-programmed gas chromatography in analytical toxicology, J. Chromatogr. It was rediscovered by the Swedish chemist Jörgen Lehmann upon the report that the tuberculosis bacterium avidly metabolized salicylic acid. Salicylic Acid is a type of beta hydroxy acid (BHA) and phenolic acid with a chemical formula C 7 H 6 O 3. Physical dangers . Khim., 43, 1988, 143-146. ass: Standard non-polar; Column diameter: 0.25 mm; Column length: 15 m; Column type: Capillary; Heat rate: 10 K/min; Start T: 130 C; End T: 290 C; End time: 10 min; Start time: 1 min; CAS no: 69727; Active phase: DB-1; Carrier gas: He; Phase thickness: 0.25 um; Data type: Normal alkane RI; Authors: Sharp, M.E., A rapid screening procedure for acidic and neutral drugs in blood by high resolution gas chromatography, J. Anal. It is obtained from the bark of the white willow and wintergreen leaves. In experiment C3.1.3.1, the thiele tube is used to determine the melting point of salicylic acid. salicyloyl-CoA + H2O -> salicylate + coenzyme A + H+. melina rosado chemistry 2612 organic chemistry lab lab report melting point of benzoic acid and salicylic acid; recrystallization of dirty benzoic acid and A melting point tube is filled with the substance to be assayed. Ambient temperatures. 6 Toxicity Expand this section. UNII-BOH38MGC8D. Flash Point. • The boiling point and melting point of Salicylic Acid are 211 °C and 315 °C, respectively • Salicylic Acid contains two hydrogen bond donors and three hydrogen bond acceptors in its molecule • The flash point of Salicylic Acid is 157 °C • Due to its lipophilic nature, its … (Literature), Soluble in alcohol, acetone, ether. 157°(315°F) Density. Visit ChemicalBook To find more Salicylic acid(69-72-7) information like chemical properties,Structure,melting point,boiling point,density,molecular formula,molecular weight, physical properties,toxicity information,customs codes. ; Tsypyshev, O.Yu., Gas chromatographic determination of the products of the synthesis of chlorine-substituted salicylic acids, Zh. Articles of Salicylic acid are included as well. Salicylic acid allows cells of the epidermis to more readily slough off. Guidechem provides Salicylic acid chemical database query, including CAS registy number 69-72-7, Salicylic acid MSDS (Material Safety Data Sheet), nature, English name, manufacturer, function/use, molecular weight, density, boiling point, melting point, structural formula, etc. Salicylic acid is a lipophilic mono-hydroxybenzoic acid, a type of phenolic acid, and a beta-hydroxy acid (BHA). 1 Structures Expand this section. More soluble in boiling water. Sat. Refractive Index : n/a. Salicylic acid, propionate. 2005-03-26. Furthermore, the melting point of salicylic acid is 158.6 °C under controlled conditions, and it undergoes sublimation over 76 °C. A melting point tube is filled with the substance to be assayed. 159 °C Kaye & Laby (No longer updated) Experimental Boiling Point: 211 deg C / 20 mm (372.9924 °C / 760 mmHg) Alfa Aesar. Soluble in carbon terachloride, benzene, propanol, absolute ethanol, acetone, toluene and ether. Salicylic acid is an organic compound having the chemical formula C 7 H 6 O 3 while benzoic acid is an organic compound having the chemical formula C 7 H 6 O 2. Display Name: Salicylic acid EC Number: 200-712-3 EC Name: Salicylic acid CAS Number: 69-72-7 Molecular formula: C7H6O3 IUPAC Name: 2-hydroxybenzoic acid ; Perrigo, B., A practical gas chromatographic screening procedure for toxicological analysis, Can. Slightly soluble in water. Example case - salicylic acid and aspirin ASA, well known for its analgesic, anti-platelet [2] and even anti-cancer effect [3], may be synthesized from SA by acid catalyzed esterification. At last,Salicylic acid(69-72 … 3 Chemical and Physical Properties Expand this section. More... Molecular Weight: 194.18 g/mol. Melting Point (°C) less than 0 (10) 0 - 100 (14) 101 - 200 (54) 201 - 300 (42) 301 - 400 (1) Color. The melting point determination apparatus is filled with paraffin and fitted with a thermometer. Chromatogr., 436, 1988, 137-172. ass: Standard non-polar; Column length: 1.8 m; Column type: Packed; Heat rate: 8 K/min; Start T: 130 C; End T: 290 C; End time: 8 min; Start time: 2 min; CAS no: 69727; Active phase: SE-30; Carrier gas: N2; Substrate: Chromosorb W; Data type: Linear RI; Authors: Perrigo, B.J. Stable. A monohydroxybenzoic acid that is benzoic acid with a hydroxy group at the ortho position. ; Ding, S.F. Substances to be avoided include oxidizing agents, strong bases, iodine, fluorine. Yojiro Tsuzuki, Masako Sawada. 5 Chemical Vendors. 6328-44-5. ; Tsypysheva, L.G. Skip to content. 4 Related Records Expand this section. umn class: Standard non-polar; Column diameter: 0.53 mm; Column length: 30 m; Column type: Capillary; Start T: 130 C; CAS no: 69727; Active phase: DB-1; Carrier gas: N2; Phase thickness: 1.5 um; Data type: Kovats RI; Authors: Japp, M.; Gill, R.; Osselton, M.D., Comparison of drug retention indices determined on packed, wide bore capillary and narrow bore capillary columns, J. Forensic Sci., 32(6), 1987, 1574-1586. umn class: Standard non-polar; Column diameter: 0.22 mm; Column length: 25 m; Column type: Capillary; Start T: 130 C; CAS no: 69727; Active phase: BP-1; Carrier gas: N2; Phase thickness: 0.25 um; Data type: Kovats RI; Authors: Japp, M.; Gill, R.; Osselton, M.D., Comparison of drug retention indices determined on packed, wide bore capillary and narrow bore capillary columns, J. Forensic Sci., 32(6), 1987, 1574-1586. umn class: Standard non-polar; Column diameter: 0.53 mm; Column length: 25 m; Column type: Capillary; Start T: 130 C; CAS no: 69727; Active phase: BP-1; Carrier gas: N2; Phase thickness: 1 um; Data type: Kovats RI; Authors: Japp, M.; Gill, R.; Osselton, M.D., Comparison of drug retention indices determined on packed, wide bore capillary and narrow bore capillary columns, J. Forensic Sci., 32(6), 1987, 1574-1586. umn class: Standard non-polar; Column type: Packed; Start T: 200 C; CAS no: 69727; Active phase: OV-1; Data type: Kovats RI; Authors: Berninger, H.; Moller, M.R., Retentionsindices zur gaschromatographischen Identifizierung von Arzneimitteln, Arch. off-white (3) white (9) yellow (1) Feature. A correlation was observed between the solubility and … This article is cited by 1 publications. ; Hua, R.L. Contents. NIST Mass Spectrometry Data Center., 2011. http://www.medchemexpress.com/milnacipran-hydrochloride.html, https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:16914, ACD/Labs Percepta Platform - PhysChem Module, US Environmental Protection Agency’s EPISuite™, Compounds with the same molecular formula, Search Google for structures with same skeleton, 211 deg C / 20 mm (372.9924 °C / 760 mmHg), 211 °C / 20 mm Hg (372.9924 °C / 760 mmHg), 211 C / 20 mmHg (372.9924 °C / 760 mmHg), 211 °C / 20 mmHg (372.9924 °C / 760 mmHg), 211 °C / 20 mm (372.9924 °C / 760 mmHg), 211 C / 20 mmHg (372.9924 °C / 760 mmHg) This lipophilic monohydroxybenzoic acid is a derivative of salicin metabolism. Sensitive to light. Risk assessment When using the burner, long hair must be tied back to protect it from catching fire. the melting point of salicylic acid as stated in my text is 159 celsius. The first patient made a dramatic recovery. A MULTI-PURPOSE COMMUNITY SITE. ; Suleimamova, R.A.; Naimushin, A.I. Salicylic acid is a natural product extract from Willow bark, well known as an antiinflammatory inhibitor of cyclooxygenase activity. Reacts with strong oxidants. ; Salicylic acid (from Latin salix, willow tree, from the bark of which the substance used to be obtained) is a monohydroxybenzoic acid, a type of phenolic acid and a beta hydroxy acid. Dust explosion possible if in powder or granular form, mixed with air. Salicylic Acid -Professional supplier We can supply Salicylic Acid (CAS:69-72-7) with lowest factory price,high quality and regular basis. Chemsrc provides Salicylic acid(CAS#:69-72-7) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Experiment set-up. Shop a large selection of Salicylic Acid products and learn more about Salicylic Acid (Crystalline/USP), Fisher Chemical. Melting point. , prices, Price, high quality and regular basis, bacteriostatic and fungicidal properties tried PAS as an inhibitor. 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